The present study investigated the feasibility and effectiveness of blue-IRIS in living corneal tissue by using 400-nm femtosecond laser pulses with 1-nJ pulse energy, 80-MHz repetition rate and 100-fs pulse duration. Blue-IRIS induced refractive changes up to 0.037 in the corneal stroma at fast scanning speeds, providing a possible alternative method of noninvasively altering corneal power.
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